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dc.contributor.authorRiera, José-
dc.contributor.authorRodríguez, René-
dc.contributor.authorTeresa Carcedo, María-
dc.contributor.authorM. Campa, Víctor-
dc.contributor.authorRamos, Sofía-
dc.date.accessioned2026-01-19T12:48:26Z-
dc.date.available2026-01-19T12:48:26Z-
dc.date.issued2007-06-26-
dc.identifier.citation- Riera, J; Rodriguez, R; Carcedo, MT; Campa, VM; Ramos, S; Lazo, PS. Isolation and characterization of nudC from mouse macrophages, a gene implicated in the inflammatory response through the regulation of PXF-AH(I) activity. FEBS Lett. 2007. 581. (16). p. 3057-3062. DOI: 10.1016/j.febslet.2007.05-065.es_ES
dc.identifier.issn1873-3468-
dc.identifier.urihttps://ria.asturias.es/RIA/handle/123456789/14914-
dc.description.abstractWe report the characterization of a cDNA induced in mouse macrophages that encodes a 332-amino acid protein with extensive sequence identity with members of the mammalian nudC-like genes. The interaction between mNUDC and the regulatory b subunit of platelet activating factor acetylhydrolase I (PAF-AH(I)) shown in this article indicates a new function of NUDC. Thus, we show that NUDC increases the catalytic activity of PAF-AH(I) and that this regulatory activity is located in the carboxyl terminal half of the protein which is highly conserved. This suggests a novel function for mammalian nudC-like genes as anti-inflammatory proteins.es_ES
dc.description.sponsorshipInstituto de Investigación Sanitaria del Principado de Asturias (ISPA)es_ES
dc.language.isoenes_ES
dc.publisherElsevier B.V. on behalf of the Federation of European Biochemical Societieses_ES
dc.rightsAtribución-NoComercial 3.0 España*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/es/*
dc.subjectMonocytes/macrophageses_ES
dc.subjectInflammationes_ES
dc.subjectPlatelet activating factor acetylhydrolasees_ES
dc.subjectnudCes_ES
dc.titleIsolation and characterization of <i>nudCi> from mouse macrophages, a gene implicated in the inflammatory response through the regulation of PAF-AH(I) activityes_ES
dc.typeArtículoes_ES
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