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Por favor, use este identificador para citar o enlazar este documento: https://ria.asturias.es/RIA/handle/123456789/2721
Título : Individual increase in inbreeding allows estimating effective sizes from pedigrees
Autor : Gutiérrez, Juan P.
Cervantes, Isabel
Molina, Antonio
Valera, Mercedes
Goyache, Félix
Palabras clave : Effective size
Increase in inbreeding
Overlapped generation
Genetic contribution
Fecha de publicación : jul-2008
Editorial : EDP Sciences
Citación : Gutiérrez, Juan Pablo; Cervantes, Isabel; Molina, Antonio; Valera, Mercedes; Goyache, Félix. Individual increase in inbreeding allows estimating effective sizes from pedigrees. Genetics Selection Evolution. 2008; 40 (4): 359-378.
Resumen : We present here a simple approach to obtain reliable estimates of the effective population size in real world populations via the computation of the increase in inbreeding for each individual (delta F(i)) in a given population. The values of delta F(i) are computed as t-root of 1 - (1 - F(i)) where F(i) is the inbreeding coefficient and t is the equivalent complete generations for each individual. The values of delta F computed for a pre-defined reference subset can be averaged and used to estimate effective size. A standard error of this estimate of N(e) can be further computed from the standard deviation of the individual increase in inbreeding. The methodology is demonstrated by applying it to several simulated examples and to a real pedigree in which other methodologies fail when considering reference subpopulations. The main characteristics of the approach and its possible use are discussed both for predictive purposes and for analyzing genealogies.
URI : http://ria.asturias.es/RIA/handle/123456789/2721
ISSN : 0999-193X
Aparece en las colecciones: Agroalimentación y Ganadería
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