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Por favor, use este identificador para citar o enlazar este documento: https://ria.asturias.es/RIA/handle/123456789/2603
Título : Vascular Calcification in Patients with Chronic Kidney Disease: Types, Clinical Impact and Pathogenesis
Autor : Rodríguez-García, Minerva
Cabezas-Rodríguez, Iván
López-Ongil, Susana
Díaz-López, Bernardino
Cannata Andía, Jorge B.
Palabras clave : Vascular calcification
Chronic kidney disease
Secondary hyperparathyroidism
Bone loss vascular-bone links
Fecha de publicación : 2011
Editorial : Karger AG
Citación : Med Princ Pract.2011;20:203–212
Resumen : Vascular calcification plays a major role in cardiovascular disease, which is one of the main causes of mortality in chronic kidney disease patients. Vascular calcification is determined by prevalent traditional and uraemia-related (non-traditional) risk factors. It occurs mainly in the arteries, which are classified into three types according to their size and structural characteristics. In addition, vascular calcification has been associated with bone loss and fractures in chronic kidney disease patients and the general population, stressing the fact that both disorders can share pathogenetic pathways. The strategies to control vascular calcification involve several measures, chief among them the control of hyperphosphataemia. Furthermore, it has been recently described that strategies that reduce bone resorption and increase bone mineralization may decrease the risk of vascular calcifications;however, this approach still remains controversial. The mechanisms involved in vascular calcification are complex and not yet fully understood. Phosphorus plays a major role,while other factors related to bone formation have been recently identified.
URI : https://ria.asturias.es/RIA/handle/123456789/2603
ISSN : 1011-7571
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